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Search Results for " farnesyl diphosphate synthase "

Targets Recommended: Others Antibacterial

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10586L	BPH-1358 NSC50460	Others; Antibacterial	Microbiology/Virology; Others
	BPH-1358 (NSC-50460) 是一种人 FPPS 和 UPPS 抑制剂，IC50值分别为 1.8 μM 和 110 nM，对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。
T8489	Minodronic acid monohydrate	Transferase	Metabolism
	Minodronic acid monohydrate 是一种法尼基二磷酸合成酶抑制剂，可作为骨吸收抑制剂。
T6373	Alendronate sodium hydrate G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax	Transferase	Metabolism
	Alendronate sodium hydrate (MK 217) 是 farnesyl diphosphate synthase 抑制剂(IC50:460 nM)。
T10586	BPH-1358 free base NSC50460 free base	Others	Others
	BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
T28151	NE21650 NE-21650,NE 21650
	NE21650, a bisphosphonate, inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase.
T22559	Alendronate sodium	Others	Others
	The compound binds and blocks farnesyl diphosphate synthase in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS). It causes macrophage apoptosis and inhibits prenylation and sterol biosynthesis in purified osteoclasts.
T15709	Lapaquistat acetate TAK-475	Others	Others
	Lapaquistat acetate is a squalene synthase inhibitor. It also blocks the conversion of farnesyl diphosphate (FPP) to squalene. Lapaquistat acetate is used to Mevalonate Kinase Deficiency (MKD), it is effective at lowering low-density lipoprotein cholester
T72587	BPH-1358 mesylate NSC50460 mesylate
	BPH-1358 mesylate (NSC50460 mesylate) 是一种有效的人FPPS 和UPPS 抑制剂，IC50值分别为 1.8 μM 和 110 nM，在体外对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。

化合物

BPH-1358

Cat.No: T10586L

Synonym: NSC50460

Target: Others, Antibacterial

Minodronic acid monohydrate

Cat.No: T8489

Synonym:

Target: Transferase

Alendronate sodium hydrate

Cat.No: T6373

Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax

Target: Transferase

BPH-1358 free base

Cat.No: T10586

Synonym: NSC50460 free base

Target: Others

NE21650

Cat.No: T28151

Synonym: NE-21650,NE 21650

Synonym: NSC50460 mesylate

Target:

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00451	FDPS Protein, Mouse, Recombinant (His) mKIAA1293,AI256750,farnesyl diphosphate	Mouse	E. coli
	FDPS Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 42.8 kDa and the accession number is Q4FJN9.